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XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-Free, Vegan - Lemon Flavour - 30 Servings

XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-Free, Vegan - Lemon Flavour - 30 Servings

Regular price $253.77 CAD
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XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-Free, Vegan - Lemon Flavour - 30 Servings

Regular price $253.77
Sale price $253.77 Regular price
Save % Sold out
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Why Choose XYMOGEN SAM-e & TMG?

Healthcare professionals across Canada trust XYMOGEN for their science-backed, high-quality supplements. This formulation is crafted with purity in mind: free from gluten, GMOs, dairy, soy, peanuts, eggs, and shellfish, making it suitable for many dietary preferences. It is also vegan and features a refreshing lemon flavour. Each bottle provides 30 servings, a convenient one-month supply. XYMOGEN is dedicated to integrative health, empowering individuals and practitioners alike with effective, evidence-based products.

What Is SAM-e & TMG?

S-Adenosylmethionine (SAM-e) and Trimethylglycine (TMG) are naturally occurring compounds that play essential roles in methylation—a key biochemical process for DNA synthesis, detoxification, and neurotransmitter production. XYMOGEN SAM-e & TMG delivers 400 mg of SAM-e and 600 mg of TMG per serving to support these critical pathways. This formula is designed for those seeking targeted methylation support in their daily wellness routine.

Top Ingredients: SAM-e and TMG

SAM-e (400 mg): SAM-e is a methyl donor involved in over 100 biochemical reactions, including the methylation of DNA, proteins, and phospholipids. It is critical for neurotransmitter synthesis and maintaining cellular membrane fluidity. XYMOGEN uses a stable, enteric-coated form to ensure optimal absorption.

TMG (600 mg): Trimethylglycine, also known as betaine, is a methyl donor that supports homocysteine metabolism. It works synergistically with SAM-e to sustain methylation cycles and promote liver function. TMG is also involved in osmoregulation and cellular hydration.

The combination of SAM-e and TMG provides a comprehensive approach to methylation support, addressing both methyl donation and recycling.

Key Benefits of SAM-e & TMG Supplementation

Methylation is involved in numerous physiological functions, and adequate levels of SAM-e and TMG may help maintain optimal cellular and metabolic health.*

  • Cellular & Metabolic Function: SAM-e and TMG support biochemical pathways involved in cell health, nutrient metabolism, and energy processes.*
  • Neurotransmitter & Liver Support: SAM-e contributes to the synthesis of neurotransmitters like serotonin and dopamine, while TMG supports glutathione production, which aids liver detoxification pathways.*
  • Glutathione Production: TMG is a methyl donor that helps recycle homocysteine to methionine, supporting the body's antioxidant defences.*

These benefits make SAM-e & TMG a valuable addition for those focussed on liver health, mood balance, and overall vitality.

How to Incorporate SAM-e & TMG Into Your Routine

For best results, take XYMOGEN SAM-e & TMG consistently as part of your daily supplement regimen. It can be taken alongside a balanced diet and other supplements, but avoid combining with high-dose folate or other methyl donors unless directed by a professional. Store in a cool, dry place away from direct sunlight. The recommended serving is one capsule daily, preferably on an empty stomach. Always follow the dosage instructions on the label or as advised by your healthcare practitioner.

FAQs About SAM-e and TMG

Who can benefit from SAM-e & TMG?

Individuals with methylation imbalances, those supporting liver detoxification, or anyone looking to maintain healthy neurotransmitter levels may find this supplement beneficial. It is also popular among those with MTHFR gene variations that affect methylation efficiency.

How should I take SAM-e & TMG?

The recommended serving is one capsule daily, preferably on an empty stomach. Always follow the dosage instructions on the label or as advised by your healthcare practitioner.

Are there any side effects?

SAM-e and TMG are generally well-tolerated. Some individuals may experience mild gastrointestinal discomfort or nausea. It is advisable to start with a lower dose and increase gradually. Consult your healthcare provider before use, especially if you are pregnant, nursing, or taking medication.

*These statements have not been evaluated by Health Canada. This product is not intended to diagnose, treat, , or prevent any disease. Always read the label and follow directions for use.

Delivery in Canada

Orders are prepared with clear Canada delivery expectations from the product page through dispatch. Delivery estimates are shown before checkout where available, and tracking details are sent after the order leaves fulfilment so customers can follow the parcel and plan around the expected arrival window.

Returns and support

Vitamin4CA offers straightforward post-purchase support with a clear returns process. Please check the store returns policy before sending an item back, as final eligibility may depend on product condition, packaging integrity and whether the return request is started within the stated return window.

How to choose

Use the product description, ingredient list, serving information and available variants to compare supplement options. Always check the full ingredient list, directions for use and any allergen information on the product packaging before taking any dietary supplement.

Ingredients and important information

Ingredient lists and formulations may vary by batch or supplier. Always check the product packaging for the most up-to-date information. Dietary supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily intake. If you are pregnant, nursing, taking medication or have a medical condition, consult your healthcare professional before use.

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  • Free standard deliveryUsually 2–7 business days to Canada, after 1–3 days to prepare
  • 30-day returnsOn unopened items in original packaging
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Buying guide and questions

Supplement guide

XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-Free, Vegan - Lemon Flavour - 30 Servings at Vitamin4CA

Why Choose XYMOGEN SAM-e & TMG?Healthcare professionals across Canada trust XYMOGEN for their science-backed, high-quality supplements. This formulation is crafted with purity in mind: free from gluten, GMOs, dair...

Category Blended Vitamin & Mineral Supplements
Delivery area Canada
Checkout Secure checkout
Brand XYMOGEN
Price $253.77
Availability In stock
allergen-freebetainecellular healthdetoxificationdietary supplementgluten-freehomocysteineliver supportmethylation supportmood support

How to choose if this supplement fits your routine

Read the ingredient list, check the serving size and directions for use. Consider the supplement form (tablet, capsule, liquid) and whether it suits your dietary requirements. Dietary supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.

Questions about XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-Free, Vegan - Lemon Flavour - 30 Servings

Is XYMOGEN SAM-e & TMG - 400 mg SAM-e & 600 mg TMG - Methylation Support - Gluten-Free, Vegan - Lemon Flavour - 30 Servings available for Canada customers?

Yes. This product is currently available on Vitamin4CA with Canada-wide delivery.

How should I compare this with similar supplements?

Compare the active ingredients, serving size, number of servings per container, supplement form, brand reputation and price per serving. Check allergen information if relevant to your dietary needs.

Where can I find delivery and returns information?

Delivery information is shown near the add to cart area. Returns guidance is available on the product page and full terms are covered in the store returns policy.