XYMOGEN 5-MTHF Plus B12 – Bioactive Folate & Methyl B12 Supplement – Cherry Flavour – 60 Quick-Dissolve Tablets

Key Benefits of Methylfolate and Methylcobalamin

Discover Xymogen 5-Mthf Plus — Vitamin B12 and folate play essential roles in several critical bodily functions. They assist in maintaining healthy nerve cells by supporting myelin production, which insulates nerves and ensures proper signal transmission. Both nutrients are also involved in red blood cell formation and DNA synthesis. Adequate B12 levels help convert food into cellular energy, which may reduce feelings of tiredness and fatigue. Furthermore, methylation support from these nutrients helps regulate homocysteine levels, contributing to cardiovascular health.* These statements describe the nutrients’ roles in normal physiology and are not intended as claims for treating or curing any condition.

What Makes This B12 Supplement Different?

Not all B12 supplements are the same. Many contain cyanocobalamin, a synthetic form that the liver must convert into active methylcobalamin. 5-MTHF Plus B12 provides methylcobalamin directly—the form most readily utilized by the nervous system. Similarly, instead of folic acid, this formula supplies 5-MTHF (L-methylfolate), which is immediately available for methylation and can be used even by individuals with MTHFR variants. The quick-dissolve tablet format dissolves rapidly in the mouth—no water or swallowing required. This sublingual route may bypass some digestive barriers, enhancing delivery. The pleasant cherry flavour makes daily use easy and enjoyable. It is also gluten-free and free from common allergens.

Who Should Consider a Bioactive B12 and Folate Supplement?

Specific groups are more prone to low levels of these nutrients. Vegans and vegetarians often lack dietary B12, which appears naturally only in animal products. Older adults may produce less stomach acid, reducing B12 absorption from food. People with MTHFR gene variations may have difficulty converting folic acid into the active 5-MTHF form. Additionally, those experiencing fatigue, brain fog, or mood changes may benefit from supporting their methylation pathways. 5-MTHF Plus B12 provides ready-to-use forms that bypass common absorption and conversion issues, making it a practical choice for these populations.

How to Use 5-MTHF Plus B12 for Best Results

Place one tablet under the tongue or on the tongue and allow it to dissolve completely. For optimal absorption, avoid eating or drinking for a few minutes after taking it. This product is intended to be used as part of a balanced diet under the guidance of a health-care professional. Individual nutrient needs vary; a qualified practitioner can help determine the appropriate dosage for your specific circumstances. Store in a cool, dry place away from direct sunlight. If you are pregnant, breastfeeding, or taking any medications, consult a healthcare practitioner before use.

Frequently Asked Questions

Why methylcobalamin instead of cyanocobalamin?

Methylcobalamin is the biologically active coenzyme form of vitamin B12. It is directly usable by the body and plays a key role in neurological health and methylation. Cyanocobalamin contains a cyanide molecule that must be removed by the liver, making it a less efficient option for those with compromised liver function or certain genetic variations.

What is 5-MTHF folate?

5-MTHF (L-methylfolate) is the active form of folate used in methylation and neurotransmitter production. Unlike folic acid, it does not require enzymatic conversion and is therefore suitable for individuals with MTHFR gene polymorphisms who cannot process synthetic folic acid effectively.

Can I take this with other supplements?

Generally, B12 and folate complement many other nutrients, but it is best to consult a health care provider when combining multiple supplements, especially if you are on medication or have specific health conditions.

What Is 5-MTHF Plus B12 and Why Do You Need It?

For individuals seeking to support their methylation pathways, the combination of active folate and methyl B12 can be a game-changer. 5-MTHF Plus B12 by XYMOGEN delivers two biologically active nutrients: methylfolate (as 5-MTHF) and methylcobalamin (methyl B12). These are the forms your body can use directly without needing to convert synthetic versions. Methylation is a vital biochemical process that occurs billions of times per second, influencing everything from DNA synthesis to detoxification. Both folate and vitamin B12 are essential cofactors in this cycle. Without adequate levels, cellular function can suffer. This supplement is designed to support normal methylation processes and maintain healthy nervous system function.*

• Bioactive Folate & B12 Formula: Provides 5-MTHF and methylcobalamin for direct methylation support.
• Nervous System Support: Assists in maintaining healthy nerve function and cellular energy.*
• Quick-Dissolve Tablet Format: Fast-dissolving, convenient for daily use without capsules or water.
• Great-Tasting Cherry Flavour: Pleasant taste encourages consistent supplementation.
• Gluten-free & Clean Formula: Free from gluten, artificial preservatives, and common allergens.

Usage Instructions: Dissolve one tablet in the mouth daily or as directed by a health-care professional.

*This product is a Natural Health Product. Always read the label and follow directions for use. These statements have not been evaluated by Health Canada. This product is not intended to diagnose, treat, , or prevent any disease.