XYMOGEN 5-MTHF Plus B12 – Bioactive Folate & Methyl B12 Supplement – Cherry Flavor – 60 Quick-Dissolve Tablets

Understanding Vitamin B12 and Its Role

Vitamin B12, also known as cobalamin, is a water-soluble nutrient essential for red blood cell formation, neurological health, and DNA synthesis. It works closely with folate to drive the methylation cycle, a process that influences gene expression, neurotransmitter production, and detoxification. Since the body cannot produce B12, it must be obtained from food or supplements. A deficiency can result in fatigue, weakness, nerve problems, and cognitive issues—common concerns for many Canadians, particularly those with dietary restrictions or absorption challenges.

What Sets 5-MTHF Plus B12 Apart?

XYMOGEN 5-MTHF Plus B12 stands out because it delivers both methylfolate (5-MTHF) and methylcobalamin in their biologically active forms. This means your body can use them immediately without needing to convert them, bypassing common genetic bottlenecks like MTHFR. The quick-dissolve tablet melts in your mouth with a pleasant cherry flavor, making it easy to take—No swallowing capsules required. This formula is also gluten-free and trusted by healthcare professionals across Canada for integrative wellness.

How Vitamin B12 Supports Your Health

Vitamin B12 contributes to normal energy-yielding metabolism by helping convert food into usable energy. It also supports the normal function of the nervous system and contributes to normal homocysteine metabolism, which is important for cardiovascular health.* Along with folate, B12 plays a role in normal psychological function and the reduction of tiredness and fatigue.* These benefits are backed by extensive research and align with Health Canada's Natural Health Product monographs.

• Energy Support – Helps your body convert food into cellular energy
• Nervous System Health – Maintains healthy nerve cells and myelin sheaths
• Methylation & Homocysteine Balance – Supports healthy homocysteine levels with folate
• Red Blood Cell Formation – Aids in red blood cell production and oxygen transport

Who Benefits from a B12 Supplement?

Certain groups are more likely to have low B12 levels: vegans and vegetarians due to limited dietary sources, older adults (reduced absorption), individuals with digestive disorders affecting nutrient uptake, and those taking medications that interfere with B12 metabolism. People with genetic variations like MTHFR may particularly benefit from the already-methylated forms in 5-MTHF Plus B12, which bypass metabolic bottlenecks.

Choosing the Right B12 Supplement

When selecting a B12 supplement, the form matters. Cyanocobalamin is synthetic and stable but requires conversion to active methylcobalamin. Methylcobalamin is the preferred bioactive form for neurological support and is what you get in 5-MTHF Plus B12. This product also provides 5-MTHF (methylfolate), the active form of folate that works synergistically with methyl B12. Look for products that are third-party tested and gluten-free, and consider a quick-dissolve format for convenience and potential sublingual absorption.

How to Take 5-MTHF Plus B12

For best results, take one quick-dissolve tablet daily, or as directed by your healthcare practitioner. Place the tablet on your tongue and allow it to dissolve completely before swallowing. It can be taken with or without food. Consistent daily use helps maintain optimal B12 and folate levels.

Frequently Asked Questions

Can you take too much B12? B12 is water-soluble, so excess amounts are typically excreted in urine. However, stick to recommended dosages unless advised otherwise by a healthcare professional.

Is this product vegan? Yes, the ingredients are vegan-friendly. The cherry flavor is derived from natural sources.

How does this compare to cyanocobalamin? Methylcobalamin is the active coenzyme form that your body can use directly, while cyanocobalamin requires conversion and contains a cyanide moiety.

Safety Information: Always consult your healthcare practitioner before using this product, especially if you are pregnant, breastfeeding, or have a medical condition. This product is a natural health product licensed under Health Canada. Always read the label and follow directions for use. Keep out of reach of children.