THORNE Sacro-B: Saccharomyces boulardii Probiotic for Gut Health and Immune Support

Why Choose Thorne Sacro-B?

Thorne is a brand trusted by over 100 professional sports teams and is the #1 most recommended clinical brand by both consumers and healthcare practitioners, based on a 2026 independent survey. Sacro-B is a premium probiotic supplement that stands out thanks to its unique yeast strain, Saccharomyces boulardii. This clinically studied yeast is naturally resistant to stomach acid and antibiotics, making it a versatile addition to your wellness routine. Each easy-to-swallow capsule delivers 5 billion colony-forming units (CFUs) of active culture, and the shelf-stable design means No refrigeration is required—perfect for travel or daily use. Third-party certification ensures that what’s on the label matches what’s in the bottle, with No unsafe levels of contaminants.

What Is Sacro-B and How Does It Work?

Sacro-B is a yeast-based probiotic designed to support digestive health and immune function. Unlike bacterial probiotics (like Lactobacillus), Saccharomyces boulardii is a transient yeast that does not colonise the gut permanently but provides support as it passes through the digestive tract. Its natural resistance to stomach acid and antibiotics means it can be taken alongside medications without losing potency. This product is a natural health product that offers gastrointestinal support for those seeking to maintain a healthy microbiome.

How Sacro-B Supports Digestive Health

A healthy gut relies on a balanced microbiome. Saccharomyces boulardii works by encouraging the growth of beneficial gut flora while helping to maintain the integrity of the intestinal barrier. Research suggests it may help reduce the frequency and duration of occasional diarrhea, such as that associated with travel or antibiotic use. By promoting a healthy microbial environment, Sacro-B helps your digestive system function smoothly. For best results, take one capsule daily with or without food, or as directed by your healthcare practitioner. You can open the capsule and mix the powder into cool or lukewarm food or drink—avoid hot liquids as they may harm the live cultures.

Strengthening Immune Function in the Gut

Approximately 70% of your immune system resides in your gut. Sacro-B supports immune function by encouraging the production of secretory IgA (sIgA), an antibody that plays a critical role in defending against pathogens in the gastrointestinal tract. A robust sIgA response means a stronger first line of defense, helping to keep harmful organisms in check. By nurturing gut-associated lymphoid tissue (GALT), Saccharomyces boulardii contributes to overall immune resilience, making it a valuable supplement for those looking to bolster their body's natural defences.

Who Should Consider Taking Sacro-B?

Sacro-B is ideal for anyone looking to support their gut health and immune function. It is particularly beneficial for individuals experiencing occasional digestive upset, those taking antibiotics (which can disrupt gut flora), and travellers exposed to new bacteria. Vegans and vegetarians will appreciate that the capsules are free from animal-derived ingredients. However, those with compromised immune systems or central venous catheters should consult a healthcare provider before use, as yeast probiotics require special consideration in immunocompromised individuals. Keep out of reach of children. Do not use if safety seal is broken.

FAQs About Sacro-B and Saccharomyces boulardii

Is Saccharomyces boulardii safe?

Yes, for most healthy individuals. Saccharomyces boulardii has a long history of safe use as a probiotic. It is generally well-tolerated, though mild bloating may occur initially. If you have a weakened immune system or are critically ill, consult your doctor before use. Always read and follow the label directions.

How is it different from bacterial probiotics?

Unlike bacterial probiotics (e.g., Lactobacillus), Saccharomyces boulardii is a yeast. It is naturally resistant to antibiotics and stomach acid, making it a good choice when you're on antibiotics. It does not colonise the gut but provides transient support.

Does it need to be refrigerated?

No! Sacro-B is shelf-stable, so you can store it at room temperature. This makes it convenient for travel and everyday use.

How should I take Sacro-B?

Take one capsule daily with or without food, or as directed by your healthcare practitioner. You can open the capsule and mix the powder into cool or lukewarm food or drink. Avoid hot liquids as they may harm the live cultures.

*This product provides probiotic support for gastrointestinal health. Natural health product; not intended to diagnose, treat, , or prevent any disease. Always consult a healthcare practitioner before use.