Plus® 3mg L-Methylfolate Supplement – Active Methylfolate, 30 Tablets

What Is L-Methylfolate?

L-methylfolate, also called 5-methyltetrahydrofolate (5-MTHF), is the bioactive form of vitamin B9. While synthetic folic acid requires conversion by the liver, L-methylfolate is ready for your body to use immediately. This makes it a popular choice for individuals seeking a directly usable form of folate.

Each tablet of Plus® provides 3 mg (3000 mcg) of pure, active L-methylfolate (calcium L-5-methyltetrahydrofolate). It is manufactured in the United States to pharmaceutical standards and tested for purity and potency, ensuring a high-quality product every time.

L-Methylfolate vs. Folic Acid: A Comparison

Folic acid is the synthetic form of vitamin B9 used in fortified foods and many supplements. To become active, folic acid must be reduced to tetrahydrofolate by the enzyme dihydrofolate reductase, then methylated to L-methylfolate. This conversion can be inefficient in some individuals.

L-methylfolate bypasses these conversion steps, providing a direct source of active folate. It does not accumulate as unmetabolised folic acid in the bloodstream – a potential concern with high intakes of synthetic folic acid. For most people, folic acid is effective and safe. Your health care provider can help determine which form is right for you.

Product Features

• Active and bio-available – L-methylfolate is the form of folate that the body can use directly.
• Manufactured in the US – produced to pharmaceutical standards.
• Tested for purity and potency – each batch is independently verified.
• High potency – 3 mg (3000 mcg) per tablet, intended for use under medical supervision.

This product is a medical food supplement. Consult your health care provider before use, especially if you have a medical condition or are taking medication. Keep out of reach of children. Store in a cool, dry place.