Nutricology QuatreActiv Folate – 833 mcg DFE 5-MTHF (Quatrefolic) – 90 Capsules

How 5-MTHF Supports Your Health

Folate is vital for DNA synthesis, red blood cell production, and homocysteine metabolism. Because 5-MTHF is the active form, it skips the conversion steps required with folic acid, making it especially helpful for those with MTHFR genetic variants that hinder folate processing. QuatreActiv Folate helps maintain healthy folate metabolism and cellular function, contributing to overall nutrient utilization.*

What Is QuatreActiv Folate?

This supplement provides 833 mcg DFE (dietary folate equivalents) of 5-methyltetrahydrofolate (5-MTHF) as Quatrefolic—the glucosamine salt of active folate. This fourth-generation folate offers a stable, well-absorbed source of methylated folate that supports folate-dependent biochemical processes, including cell growth and nutrient balance.* Unlike standard folic acid, which requires enzymatic conversion, 5-MTHF is immediately usable by the body, making it an efficient choice for direct folate support.

Who Should Consider This Supplement?

Many adults can benefit from adequate folate intake. This supplement is particularly useful for those with dietary restrictions (e.g., vegans, vegetarians) or genetic factors affecting folate metabolism. Women who are pregnant or planning pregnancy often need more folate, but should consult a health care practitioner. Athletes and individuals under stress may also find support for methylation and energy pathways.*

Why Quatrefolic Stands Out

Quatrefolic, the glucosamine salt of 5-MTHF, provides enhanced stability and bioavailability compared to other folate forms. Unlike synthetic folic acid—which must be converted in the liver—5-MTHF is ready for immediate cellular use. This makes QuatreActiv Folate an excellent option for superior absorption and direct support of methylation cycles. The formulation is free from common allergens, ensuring broad compatibility.

Purity and Quality You Can Trust

Nutricology upholds the highest purity standards: this supplement is free from gluten, dairy, soy, corn, nuts, egg, shellfish, fish, sesame, and yeast. It suits many dietary needs and is backed by over 45 years of expertise from Allergy Research Group and its family of brands. Each capsule delivers 833 mcg DFE (500 mcg of 5-MTHF) in a convenient, once-daily serving.

Frequently Asked Questions

What is the difference between folic acid and 5-MTHF? Folic acid is synthetic and requires conversion in the body, while 5-MTHF is the biologically active form used directly by cells.

How many capsules per serving? One capsule provides 833 mcg DFE (500 mcg 5-MTHF). The recommended serving is typically one capsule daily with food, or as directed by a health care practitioner.

Is this supplement suitable for vegans? The capsule is made from hypromellose (vegetarian-friendly). Always confirm on the label.

Can it be taken with other supplements? Generally, yes. However, consult a health care provider for personalised advice, especially if taking medications or other methylated nutrients.

* This product is a natural health product. Always read and follow the label. Consult a health care practitioner before use if you are taking medication or have a medical condition.