Natural Factors Vitamin D3 & K2 1000 IU / 120 mcg - 60 Softgels

Key Health Benefits

• Strong Bones and Teeth: Vitamin D3 supports calcium absorption, while vitamin K2 helps direct calcium to bones and teeth, contributing to the maintenance of strong bones and teeth.*
• Vascular Health: By activating matrix GLA protein (MGP), K2 helps keep calcium from accumulating in artery walls, supporting normal arterial flexibility and cardiovascular function.*
• Immune Support: Vitamin D3 plays a role in the normal function of the immune system, contributing to a healthy immune response.*
• Nerve and Muscle Function: Adequate D3 levels support normal nerve transmission and muscle contraction, essential for everyday movement.*

Recommended Dosage

Adults: Take one softgel daily with a meal containing healthy fats for optimal absorption, or as directed by a healthcare practitioner. Each softgel provides 1000 IU of vitamin D3 (cholecalciferol) and 120 mcg of vitamin K2 (as menaquinone-7, MK-7). Do not exceed recommended dose. Keep out of reach of children.

Why Take Vitamin D3 and K2 Together?

Vitamin D3 helps your body absorb calcium from food, but without sufficient vitamin K2, calcium may be deposited in soft tissues like arteries instead of bones. This combination addresses that concern. Natural Factors Vitamin D3 & K2 supplies 1000 IU of cholecalciferol (D3) and 120 mcg of menaquinone (K2, as MK-7) in one convenient softgel. Taking them together supports the body's natural calcium trafficking—D3 pulls calcium into the bloodstream, and K2 activates proteins that direct it to the skeleton and teeth while helping keep it away from vascular walls. Many health-conscious Canadians choose a combined D3+K2 supplement for this synergistic approach.

Understanding the Synergy: How D3 and K2 Work Together

Vitamin D3 increases expression of calcium-binding proteins in the intestine, enhancing absorption. Meanwhile, vitamin K2 activates two critical proteins: osteocalcin, which binds calcium to the bone matrix, and matrix GLA protein (MGP), which inhibits calcium deposition in arteries. Without sufficient K2, the calcium absorbed thanks to D3 may not be effectively utilised. The MK-7 form of K2 used here has a longer half-life than MK-4, providing sustained activation of these proteins throughout the day. This combination helps maintain normal calcium balance, supporting bone density and arterial flexibility. The result is a coordinated system that ensures calcium goes where it is needed most—strong bones and teeth—rather than accumulating where it could be problematic.

Frequently Asked Questions

Can I take vitamin D3 and K2 separately?

Yes, but taking them together ensures the calcium absorbed from D3 is properly directed by K2. A combined supplement simplifies dosing and guarantees the synergistic ratio.

What is the best time to take this supplement?

Since softgels are fat-soluble, take them with a meal containing healthy fats for maximum absorption. Many people take it with breakfast or lunch.

Are there any side effects?

When taken as directed, side effects are rare. If you are taking blood thinners (e.g., warfarin), consult a healthcare practitioner before use, as vitamin K2 may interact with anticoagulant medication. Consult a healthcare practitioner if you have kidney stones or are pregnant/breastfeeding.

Can I take this with other supplements?

Yes, it pairs well with magnesium and calcium supplements. For personalized advice, speak with a healthcare professional.

What to Look For in a D3 + K2 Supplement

Not all D3+K2 supplements are created equal. The dosage ratio matters: 1000 IU of D3 paired with 120 mcg of K2 (MK-7) is a well-studied combination for general maintenance. The form of K2 is crucial—MK-7 (as menaquinone-7) offers superior bioavailability and a longer active life compared to MK-4. Natural Factors uses highly bioavailable forms of both nutrients in a softgel format for optimal absorption. Additionally, this product is third-party tested for purity and potency, verified non-GMO, and screened for over 800 contaminants using mass spectrometry. Look for similar quality indicators when choosing your supplement, and always check for transparent labelling of ingredient sources and dosage.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, , or prevent any disease. Consult a healthcare practitioner prior to use if you are taking medication or have a medical condition.