Methylated Multivitamin - Methylated B Complex with TMG & Methylfolate - 120 Capsules

Key Ingredients & Activated Forms

• Vitamin B2 (Riboflavin 5'-Phosphate, R-5-P): An activated form of riboflavin that supports energy production and antioxidant activity.
• Vitamin B6 (Pyridoxal 5'-Phosphate, P-5P): The coenzyme form involved in neurotransmitter synthesis and homocysteine regulation.
• Vitamin B12 (Methylcobalamin and Dibencozide): Two active B12 forms. Methylcobalamin is the primary form used in methylation, while dibencozide (adenosylcobalamin) supports mitochondrial energy.
• Trimethylglycine (TMG): A methyl donor that helps reduce homocysteine levels.
• Calcium L-5-Methyltetrahydrofolate (Methylfolate): The active form of folic acid, essential for DNA synthesis and methylation.

Discover Methylated Multivitamin (Methylated — This combination ensures all B vitamins are present in forms the body can use immediately. The formula also includes coenzyme B2 (R-5-P) and B6 (P-5P), which do not require further enzymatic activation—ideal for those with genetic impairments.

How to Choose the Right MTHFR Supplement

For individuals with MTHFR mutations, selecting a supplement with methylated vitamins is critical. Standard folic acid and other inactive B vitamins may accumulate without providing benefits. Look for supplements that specify methylfolate, methylcobalamin, and other coenzyme forms. Double Wood's product contains only methylated and activated vitamins, making it ideal for this purpose. The inclusion of TMG further supports the methylation cycle. Non-GMO and gluten-free, it can be taken alongside a regular multivitamin if additional non-B vitamins are desired, but it is complete as a standalone methylated B complex.

Benefits of Methylated B complex

B vitamins play essential roles in energy metabolism, nervous system function, and red blood cell formation. In methylated forms, they may be more effectively utilized by the body. Methyl groups are crucial for methylation, a process that influences DNA repair, detoxification, and neurotransmitter production. Double Wood's methylated B complex includes B2 and B6 in their coenzyme forms, making them accessible even with genetic impairments. Adding TMG and methylfolate further supports methylation pathways. Many users report improved energy and cognitive clarity when switching from standard vitamins to methylated versions.

What is a Methylated Multivitamin?

A methylated multivitamin provides vitamins in their already-active, bio-available forms. Unlike standard vitamins that require multiple conversion steps, methylated versions are ready for immediate use—important for individuals with MTHFR gene variations who may have difficulty converting folic acid and other B vitamins. Double Wood's Methylated Multivitamin is designed for those seeking only methylated and activated vitamins, making it an excellent choice for optimizing nutrient uptake. This formula contains six methylated vitamins, including a complete B complex with B2 as R-5-P, B6 as P-5P, and B12 as methylcobalamin and dibencozide, plus TMG and methylfolate to support healthy homocysteine metabolism.

How to Take This Supplement

The recommended dosage is one capsule daily with a meal. Consistency is key. For those new to methylated supplements, starting with one capsule may be sufficient. Do not exceed the recommended dose without consulting a health-care professional. If taking other supplements, check for overlapping ingredients to avoid excessive intake of specific B vitamins.

Side Effects and Interactions

Methylated vitamins are generally well tolerated. Some individuals may experience mild nausea or digestive upset initially. Bright yellow urine from riboflavin is common and harmless. TMG and methylfolate may cause over-methylation in sensitive individuals, leading to irritability or anxiety—reduce dose or consult a professional if this occurs. This product may interact with medications for epilepsy, Parkinson's disease, and chemotherapy. Always discuss supplement use with your doctor. Pregnant or nursing women should seek medical advice before use.

Health Canada Disclaimer: These statements have not been evaluated by Health Canada. This product is not intended to diagnose, treat, , or prevent any disease.