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Designs for Health Ultra Methylated B12 + Methyl Folate - Vitamin B12 (Methylcobalamin & Adenosylcobalamin) and 5-MTHF Folate Supplement for Methylation Support (90 Capsules)

Designs for Health Ultra Methylated B12 + Methyl Folate - Vitamin B12 (Methylcobalamin & Adenosylcobalamin) and 5-MTHF Folate Supplement for Methylation Support (90 Capsules)

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Designs for Health Ultra Methylated B12 + Methyl Folate - Vitamin B12 (Methylcobalamin & Adenosylcobalamin) and 5-MTHF Folate Supplement for Methylation Support (90 Capsules)

Regular price $109.96
Sale price $109.96 Regular price
Save % Sold out
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Who Might Benefit from Vitamin B12 Supplementation?

Discover Designs Health Ultra — If you're feeling low on energy or struggling with focus, your body might be signaling a need for more B12. But not all B12 supplements are created equal—especially when it comes to absorption and effectiveness. Certain groups are at higher risk of B12 deficiency and may benefit from supplementation. Vegans and vegetarians often lack dietary B12 since it is naturally found only in animal products. Older adults frequently experience reduced stomach acid, which impairs B12 absorption from food. Individuals with digestive conditions like Crohn's disease or those who have had gastric bypass surgery may also struggle to absorb B12. Additionally, people taking medications such as metformin or proton pump inhibitors can deplete B12 levels. If you fall into any of these categories, a reliable supplement like this one can support your daily needs.

What Sets This Formula Apart?

This formula stands out by combining two bioactive forms of vitamin B12—methylcobalamin and adenosylcobalamin—with a patented, active form of folate called Quatrefolic (5-MTHF). Unlike synthetic cyanocobalamin, methylcobalamin is ready for your body to use, especially for nerve and brain health. Adenosylcobalamin is the form stored in mitochondria, where it directly supports cellular energy production. Together with 5-MTHF, the only form of folate that can cross the blood-brain barrier without conversion, this duo provides comprehensive methylation support. Each capsule delivers 2,000 mcg of B12 and 680 mcg of folate, making it a potent choice for those seeking targeted nutritional support.

How B12 and Folate Support Your Health

Vitamin B12 and folate work synergistically to support several vital functions in the body. One of their primary roles is in the methylation cycle, which helps regulate homocysteine levels—an important marker for cardiovascular health. By promoting normal homocysteine metabolism, these nutrients contribute to heart and blood vessel wellness. B12 also supports healthy nerve function and may help maintain cognitive clarity, while folate is essential for cellular division and growth. Together, they play a role in red blood cell formation, which is necessary for oxygen transport and sustained energy. Additionally, both nutrients support the immune system and help the body manage stress. As part of a balanced diet and healthy lifestyle, this supplement can help you feel your best every day.

What Is Vitamin B12 and Why Do You Need It?

Vitamin B12, also known as cobalamin, is an essential water-soluble vitamin that plays a critical role in nerve function, red blood cell formation, and DNA synthesis. It is also a key player in the methylation cycle, a biochemical process that influences everything from energy production to detoxification. Unfortunately, many people don't get enough B12 from diet alone—especially vegans, vegetarians, and older adults whose absorption declines with age. Supplementing with a high-quality B12 like Ultra Methylated B12 + Methyl Folate can help fill this gap, supporting overall vitality and long-term health.

Selecting the Right B12 Supplement

When choosing a B12 supplement, consider the form of B12, dosage, and additional ingredients. Methylcobalamin and adenosylcobalamin are bioactive forms that your body can use immediately, making them superior to synthetic cyanocobalamin for many people. The addition of folate, especially in its active form 5-MTHF, further enhances bioavailability and supports methylation. Ultra Methylated B12 + Methyl Folate is vegan, free from common allergens, and manufactured by Designs for Health, a brand trusted by functional medicine professionals. Look for third-party testing or professional endorsements to ensure quality and potency.

Recommended Dosage and How to Take

As a dietary supplement, take one capsule daily, preferably with a meal, or as directed by your healthcare professional. Each capsule provides 2,000 mcg of vitamin B12 (as methylcobalamin and adenosylcobalamin) and 680 mcg of folate (as Quatrefolic 5-MTHF). This dosage is suitable for most adults looking to support methylation, energy, and nerve health. If you have specific health concerns or are taking medications, consult your healthcare provider before starting any new supplement regimen.

Frequently Asked Questions

What is the difference between methylcobalamin and cyanocobalamin? Methylcobalamin is the active, naturally occurring form of B12 that your body can use directly, especially in the nervous system. Cyanocobalamin is a synthetic form that requires conversion in the liver, which may be less efficient for some people. Ultra Methylated B12 + Methyl Folate uses only bioactive forms to ensure optimal utilisation.

Can I take this if I am pregnant or nursing? While folate is especially important during pregnancy, consult your doctor before taking any supplement while pregnant or breastfeeding.

Product Highlights

  • Vegan, bioactive vitamin B12 (methylcobalamin + adenosylcobalamin) and active folate (5-MTHF via Quatrefolic)
  • Supports methylation, homocysteine regulation, nerve health, and cellular energy
  • 2,000 mcg B12 and 680 mcg folate per capsule
  • No gluten, dairy, or soy; free from artificial additives
  • Trusted by functional medicine professionals

Usage Instructions: Take one capsule daily with a meal or as recommended by your healthcare provider. Store in a cool, dry place. Keep out of reach of children.

This product is a natural health product licensed by Health Canada. Always read and follow the label. Consult a healthcare practitioner if symptoms persist or worsen.

Delivery in Canada

Orders are prepared with clear Canada delivery expectations from the product page through dispatch. Delivery estimates are shown before checkout where available, and tracking details are sent after the order leaves fulfilment so customers can follow the parcel and plan around the expected arrival window.

Returns and support

Vitamin4CA offers straightforward post-purchase support with a clear returns process. Please check the store returns policy before sending an item back, as final eligibility may depend on product condition, packaging integrity and whether the return request is started within the stated return window.

How to choose

Use the product description, ingredient list, serving information and available variants to compare supplement options. Always check the full ingredient list, directions for use and any allergen information on the product packaging before taking any dietary supplement.

Ingredients and important information

Ingredient lists and formulations may vary by batch or supplier. Always check the product packaging for the most up-to-date information. Dietary supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily intake. If you are pregnant, nursing, taking medication or have a medical condition, consult your healthcare professional before use.

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  • Free standard deliveryUsually 2–7 business days to Canada, after 1–3 days to prepare
  • 30-day returnsOn unopened items in original packaging
  • Secure checkoutProcessed by Shopify with major cards accepted
  • Real supportEmail or phone, answered by our team

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Buying guide and questions

Supplement guide

Designs for Health Ultra Methylated B12 + Methyl Folate - Vitamin B12 (Methylcobalamin & Adenosylcobalamin) and 5-MTHF Folate Supplement for Methylation Support (90 Capsules) at Vitamin4CA

Who Might Benefit from Vitamin B12 Supplementation?Discover Designs Health Ultra — If you're feeling low on energy or struggling with focus, your body might be signaling a need for more B12. But not all B12 supplement...

Category Vitamin B12 Supplements
Delivery area Canada
Checkout Secure checkout
Brand Designs for Health
Price $109.96
Availability In stock
5-MTHFadenosylcobalaminB12cardiovascular supportDesigns for Healthenergy supportfolatemethylationmethylcobalaminnerve health

How to choose if this supplement fits your routine

Read the ingredient list, check the serving size and directions for use. Consider the supplement form (tablet, capsule, liquid) and whether it suits your dietary requirements. Dietary supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.

Questions about Designs for Health Ultra Methylated B12 + Methyl Folate - Vitamin B12 (Methylcobalamin & Adenosylcobalamin) and 5-MTHF Folate Supplement for Methylation Support (90 Capsules)

Is Designs for Health Ultra Methylated B12 + Methyl Folate - Vitamin B12 (Methylcobalamin & Adenosylcobalamin) and 5-MTHF Folate Supplement for Methylation Support (90 Capsules) available for Canada customers?

Yes. This product is currently available on Vitamin4CA with Canada-wide delivery.

How should I compare this with similar supplements?

Compare the active ingredients, serving size, number of servings per container, supplement form, brand reputation and price per serving. Check allergen information if relevant to your dietary needs.

Where can I find delivery and returns information?

Delivery information is shown near the add to cart area. Returns guidance is available on the product page and full terms are covered in the store returns policy.